Symposium

19th Interdisciplinary Cerebrovascular Symposium

Date
17/08/2023
A partir de
800.00 CHF

The Interdisciplinary Cerebrovascular Symposium has become a premier meeting, gathering experts with different backgrounds: geneticists, biologists, clinicians, engineers and more recently, data analysts and modellers using AI with a common aim to better understand cerebrovascular pathophysiology and develop new tools to diagnose and treat cerebrovascular diseases. The first ICS took place in Geneva in 2004 and was organised by Prof Daniel A. Rüfenacht, Prof Pedro Lylyk and Prof Makoto Ohta. 

The 2023 opus will cover physiology of the cerebrovascular autoregulation and implications in ischemic and haemorrhagic stroke, as well as mechanisms of vessel wall remodelling, aneurysm formation and progression, arterio-venous malformation and arterio-venous fistula natural history modelling and treatments, as well as discussions on cavernous angioma, vasospasm, hydrocephalus and cerebrovascular disautonomy induced by trauma. The sessions will focus on key questions addressed by experts from different backgrounds ending with a moderated roundtable discussion. It has been decided to leave enough time between the sessions and organise social events to promote collaborations.

Prof. Philippe Bijlenga, Prof. Sven Hirsch, Dr. Sandrine Morel, Prof. Paolo Machi, Dr Emmanuel Carrera, Dr. Julien Haemmerli, Prof. Karl Schaller

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The meeting will not be streamed.

Credits: 24 credits CME

Price:

Congress Registration: CHF 800.-
Friday night dinner CHF 100.-
Saturday night dinner CHF 100.-


Venue

Forum Geneva
Rue de Lausanne 11-19
1201 Geneva

46.212387980744, 6.1443643

Forum Geneva

Rue de Lausanne 11-19
1201 Genève
Suisse


Program

Tursday 17 August 2023
08:00

Registration & coffee

8h30
Welcome

8h30-9h15
Cerebrovascular pathology major challenges and tools to succeed
Prof. Jonathan Rosand, neurologist, clinician-scientist and Professor of Neurology, Harvard Medical School. 

09:30

Ischemic stroke

9h30-9h42
Federating and data share in clinical neurosciences
Philippe Ryvlin

09h45-09h57    
Genetics of ischemic stroke
Stéphanie Debette 

10h00-10h12    
Anatomical Tracings of Lesions After Stroke (ATLAS) 5 key messages   
Thomas Wälchli

10h15-10h27    
Blood biomarkers of underlying stroke etiology    

Mira Katan

10h30-10h42
Molecular mechanisms of different types of stroke from expression profiling of retrieved thrombi
Vincent Tutino

10h45-11h00    
Break    

11:00

Ischemic stroke and modeling

11h00-11h12    
Genetic cause of childhood stroke    
Joel Fluss

11h15-11h27    
ER-mitochondria contact sites: a potential therapeutic target for ischemic stroke    
Yves Gouriou

11h30-11h42    
Cerebrovascular unit, blood brain barrier and ischemia    
Susanne Wegener

11h45-11h57    
Mathematical models of the cerebral microcirculation and oxygen transport to tissue
Stephen J Payne

12h00-12h15
Break    

12:15

Challenges and sharing experience

12h15-12h27
Effective and ineffective medical and interventional treatments of vertebral artery ischemic disease   
Patrik Michel

12h30-12h42
Surgical options for extracranial vertebral artery ischemic disease
Fady Charbel

12h45-12h57
Future directions in medical VR training: Challenges and opportunities
Paul Zikas/Steve Kateros

13h00-13h12
Personalised solution for patient care, education and developments
Mathieu Sanchez

13h15-14h00
Lunch & Poster Discussions    

14h00-14h45
Degenerative brain diseases and effect on microcirculation
Hugh Markus

15:00

Hemorrhagic stroke

15h00-15h12    
Genetics of ICH and ERICH study    
Stacie Demel

15h15-15h27
Causal ICH classification (CLAS-ICH)    
Martina Göldlin

15h30-15h42
Minimally invasive hematoma removal
Raphael Guzman

15h45-16h15
Break

16:15

Cavernoma 

16h15-16h27
Natural history and clinical management
Philipp Damman

16h30-16h42
Brain stem cavernoma management
Amir Dehdashti

16h45-16h57
Cavernoma inflammation and microbiot
Andrea Cardia

17h00-18h30
Informal discussion & demos in the lobby

Free evening 

Friday 18 August 2023
08:00

Cofee

8h15
Welcome

08:30

Intracranial aneurysms What do we know, do and should expect

Gabriel Rinkel

09:30

IA initiation

09h30-09h42
Genetics of intracranial aneurysms    
Mark Bakker

09h45-09h57
Primary cilia control endothelial permeability by regulating expression and location of junction proteins    
Mannekomba Diagbouga

10h00-10h12
Intracranial aneurysm, sex-dependent characteristics
Sandrine Morel

10h15-10h27
Sub Arachnoïd Haemorrhage Flora Japan Project
Akio Morita

10h30-11h00
Break

11:00

Detection and classification of IA  

11h00-11h12
Genetics of familial aneurysm     
Richard Redon

11h15-11h27
Integrating data to model a multifactorial disease - ontology and database representation
Alban Gaignard

11h30-11h42
Decision upport using Bayesian networks
Georg Spinner

11h45-11h57
Clinical management of unruptured intracranial aneurysms: lessons learned from the pathobiology of the aneurysm wall
Joanna Frösen

12h00-12h15
Break

12:15

Aneurysm up-stream vascular network and flow

12h15-12h27
Synthetic database of arterial network and its variability
Hitomi Anzaï

12h30-12h42
Willis Polygon geometry
Norman Juchler

12h45-12h57
Experiment-based super-resolution in intracranial aneurysms using direct data assimilation
Franziska Gaidzik

13h00-13h12
Cerebral blood flow from MRI
Sepideh Amin-Hanjani

13h15-14h00
Lunch & Poster Blitz    

14h00-14h45
Current state of AI in Medicine
Pietro Lio

15:00

IA stabilisation

15h00-15h12
Hemodynamic stress and endothelial responses in cerebral aneurysms
Naoki Kaneko 

15h15-15h27
EC cells replication and migration
Makoto Ohta

15h30-15h42
Imaging markers, MRI micelles
Eric Allémann

15h45-15h57
Modelling the mechanobiology of intracranial aneurysm evolution
Paul Watton

16h00-16h15
Break

16:15

IA progression

16h15-16h27
Vessel wall structure changes
Rikka Tulamo

16h30-16h42
Circulating gene expression signatures as molecular markers for intracranial aneurysm detection and risk stratification
Vincent Tutino

16h45-16h57
Emerging hemodynamic markers of (un)stable aneurysms: Refined ingredients or just more alphabet soup?
David Steinman

17h00-17h12
Ultrastructural modeling of wall-thinning and thickening process of intracranial aneurysms
Takanobu Yagi

17h30-18h30
Informal discussion & demos in the lobby    

19h30
Dinner Place Neuve - Lyric Restaurant

Saturday 19 August 2023
08:00

Coffee

8h15
Welcome

08:30

The cerebrovascular system in the Human Virtual Twin

Alfons Hoekstra

09:30

IA rupture and treatments

09h30-09h42
Biomechanics of IA rupture
Anne Robertson

09h45-09h57
Intravascular Imaging: High resolution microscopy of the cerebrovasculature and beyond
Matt Gounis

10h00-10h12
Genetics of SAH outcome
Ben Gaastra

10h15-10h27
Life experience regarding intracranial aneurysms management
Nobuyuki Sakai 

10h30-11h00
Break

11:00

Hydrocephalus

11h00-11h12
Initial experience using the eShunt device for the treatment of Normal Pressure Hydrocephalus. (NPH)
Charles Matouk

11h15-11h27
Water and solute dynamic in the brain
Stephen J Payne

11h30-11h42
Craniospinal Compliance. Original conception, 50 years of lessons learned, and new approaches for non-invasive measurement
Andreas Spiegelberg

11h45-11h57
Deferiprone Iron chelation to improve Outcome after SAH - UDISCO
David Hasan

12h00-12h15
Break

12:15

Short communication

12h15-12h25
Beyond the border. Dual training in neurovascular surgery
Anatoly V. Bervitskiy

12h25-12h35
Novel thin-film implants for the treatment of intracranial aneurysms
Prasanth Velvaluri

12h35-12h45
A novel method for brain aneurysms CFD analysis after flow diverter stent implantation based on micro-CT reconstruction
Philippe Reymond

12h45-12h55
Intraoperative LASER Speckle contrast imaging to assess vessel flow in neurosurgery
Johannes Goldberg

12h55-13h05
Coincidental cerebral aneurysms and intracranial tumours
Oleg M. Andrushkevich

13h05-13h15
TBC
Janneck Stahl

13h15:14h00
Lunch & Poster Discussions






 

14:00

Simulating IA initiation and progression

Jay Humphrey

15:00

Vasospasm

15h00-15h12
Genetics of vasospasm and DCI in aneurysmal subarachnoid hemorrhage
Elisa Cuadrado-Godia

15h15-15h27
Cerebrovascular vasospasm modelling
Giulia Pederzani

15h30-15h42
CBF autoregulation after SAH:  do we need it at all ?
Marek Czosnyka

15h45-15h57
Induced Suppression of Platelets Activity in aSAH Management - iSPASM
David Hasan

16h00-16h15
Break






 

16:15

AVM

16h15-16h27    
Why AVMs    
Ivan Radovanovic

16h30-16h42
Biomechanics of AVM
Ali Alaraj

16h45-16h57
Perspectives on robotics and digital technologies in neuro intervention

Vitor Mendes Pereira

17h00-17h12
Surgical treatment of AVM using Mixed Reality
Julien Haemmerli

17h15-17h30
Closing remarks
Karl Schaller & Philippe Bijlenga

17h30-18h30
Informal discussion & demos in the lobby    

19h30
Lake Dinner - Restaurant de la Plage

08:00

Registration & coffee

8h30
Welcome

8h30-9h15
Cerebrovascular pathology major challenges and tools to succeed
Prof. Jonathan Rosand, neurologist, clinician-scientist and Professor of Neurology, Harvard Medical School. 

09:30

Ischemic stroke

9h30-9h42
Federating and data share in clinical neurosciences
Philippe Ryvlin

09h45-09h57    
Genetics of ischemic stroke
Stéphanie Debette 

10h00-10h12    
Anatomical Tracings of Lesions After Stroke (ATLAS) 5 key messages   
Thomas Wälchli

10h15-10h27    
Blood biomarkers of underlying stroke etiology    

Mira Katan

10h30-10h42
Molecular mechanisms of different types of stroke from expression profiling of retrieved thrombi
Vincent Tutino

10h45-11h00    
Break    

11:00

Ischemic stroke and modeling

11h00-11h12    
Genetic cause of childhood stroke    
Joel Fluss

11h15-11h27    
ER-mitochondria contact sites: a potential therapeutic target for ischemic stroke    
Yves Gouriou

11h30-11h42    
Cerebrovascular unit, blood brain barrier and ischemia    
Susanne Wegener

11h45-11h57    
Mathematical models of the cerebral microcirculation and oxygen transport to tissue
Stephen J Payne

12h00-12h15
Break    

12:15

Challenges and sharing experience

12h15-12h27
Effective and ineffective medical and interventional treatments of vertebral artery ischemic disease   
Patrik Michel

12h30-12h42
Surgical options for extracranial vertebral artery ischemic disease
Fady Charbel

12h45-12h57
Future directions in medical VR training: Challenges and opportunities
Paul Zikas/Steve Kateros

13h00-13h12
Personalised solution for patient care, education and developments
Mathieu Sanchez

13h15-14h00
Lunch & Poster Discussions    

14h00-14h45
Degenerative brain diseases and effect on microcirculation
Hugh Markus

15:00

Hemorrhagic stroke

15h00-15h12    
Genetics of ICH and ERICH study    
Stacie Demel

15h15-15h27
Causal ICH classification (CLAS-ICH)    
Martina Göldlin

15h30-15h42
Minimally invasive hematoma removal
Raphael Guzman

15h45-16h15
Break

16:15

Cavernoma 

16h15-16h27
Natural history and clinical management
Philipp Damman

16h30-16h42
Brain stem cavernoma management
Amir Dehdashti

16h45-16h57
Cavernoma inflammation and microbiot
Andrea Cardia

17h00-18h30
Informal discussion & demos in the lobby

Free evening 

08:00

Cofee

8h15
Welcome

08:30

Intracranial aneurysms What do we know, do and should expect

Gabriel Rinkel

09:30

IA initiation

09h30-09h42
Genetics of intracranial aneurysms    
Mark Bakker

09h45-09h57
Primary cilia control endothelial permeability by regulating expression and location of junction proteins    
Mannekomba Diagbouga

10h00-10h12
Intracranial aneurysm, sex-dependent characteristics
Sandrine Morel

10h15-10h27
Sub Arachnoïd Haemorrhage Flora Japan Project
Akio Morita

10h30-11h00
Break

11:00

Detection and classification of IA  

11h00-11h12
Genetics of familial aneurysm     
Richard Redon

11h15-11h27
Integrating data to model a multifactorial disease - ontology and database representation
Alban Gaignard

11h30-11h42
Decision upport using Bayesian networks
Georg Spinner

11h45-11h57
Clinical management of unruptured intracranial aneurysms: lessons learned from the pathobiology of the aneurysm wall
Joanna Frösen

12h00-12h15
Break

12:15

Aneurysm up-stream vascular network and flow

12h15-12h27
Synthetic database of arterial network and its variability
Hitomi Anzaï

12h30-12h42
Willis Polygon geometry
Norman Juchler

12h45-12h57
Experiment-based super-resolution in intracranial aneurysms using direct data assimilation
Franziska Gaidzik

13h00-13h12
Cerebral blood flow from MRI
Sepideh Amin-Hanjani

13h15-14h00
Lunch & Poster Blitz    

14h00-14h45
Current state of AI in Medicine
Pietro Lio

15:00

IA stabilisation

15h00-15h12
Hemodynamic stress and endothelial responses in cerebral aneurysms
Naoki Kaneko 

15h15-15h27
EC cells replication and migration
Makoto Ohta

15h30-15h42
Imaging markers, MRI micelles
Eric Allémann

15h45-15h57
Modelling the mechanobiology of intracranial aneurysm evolution
Paul Watton

16h00-16h15
Break

16:15

IA progression

16h15-16h27
Vessel wall structure changes
Rikka Tulamo

16h30-16h42
Circulating gene expression signatures as molecular markers for intracranial aneurysm detection and risk stratification
Vincent Tutino

16h45-16h57
Emerging hemodynamic markers of (un)stable aneurysms: Refined ingredients or just more alphabet soup?
David Steinman

17h00-17h12
Ultrastructural modeling of wall-thinning and thickening process of intracranial aneurysms
Takanobu Yagi

17h30-18h30
Informal discussion & demos in the lobby    

19h30
Dinner Place Neuve - Lyric Restaurant

08:00

Coffee

8h15
Welcome

08:30

The cerebrovascular system in the Human Virtual Twin

Alfons Hoekstra

09:30

IA rupture and treatments

09h30-09h42
Biomechanics of IA rupture
Anne Robertson

09h45-09h57
Intravascular Imaging: High resolution microscopy of the cerebrovasculature and beyond
Matt Gounis

10h00-10h12
Genetics of SAH outcome
Ben Gaastra

10h15-10h27
Life experience regarding intracranial aneurysms management
Nobuyuki Sakai 

10h30-11h00
Break

11:00

Hydrocephalus

11h00-11h12
Initial experience using the eShunt device for the treatment of Normal Pressure Hydrocephalus. (NPH)
Charles Matouk

11h15-11h27
Water and solute dynamic in the brain
Stephen J Payne

11h30-11h42
Craniospinal Compliance. Original conception, 50 years of lessons learned, and new approaches for non-invasive measurement
Andreas Spiegelberg

11h45-11h57
Deferiprone Iron chelation to improve Outcome after SAH - UDISCO
David Hasan

12h00-12h15
Break

12:15

Short communication

12h15-12h25
Beyond the border. Dual training in neurovascular surgery
Anatoly V. Bervitskiy

12h25-12h35
Novel thin-film implants for the treatment of intracranial aneurysms
Prasanth Velvaluri

12h35-12h45
A novel method for brain aneurysms CFD analysis after flow diverter stent implantation based on micro-CT reconstruction
Philippe Reymond

12h45-12h55
Intraoperative LASER Speckle contrast imaging to assess vessel flow in neurosurgery
Johannes Goldberg

12h55-13h05
Coincidental cerebral aneurysms and intracranial tumours
Oleg M. Andrushkevich

13h05-13h15
TBC
Janneck Stahl

13h15:14h00
Lunch & Poster Discussions






 

14:00

Simulating IA initiation and progression

Jay Humphrey

15:00

Vasospasm

15h00-15h12
Genetics of vasospasm and DCI in aneurysmal subarachnoid hemorrhage
Elisa Cuadrado-Godia

15h15-15h27
Cerebrovascular vasospasm modelling
Giulia Pederzani

15h30-15h42
CBF autoregulation after SAH:  do we need it at all ?
Marek Czosnyka

15h45-15h57
Induced Suppression of Platelets Activity in aSAH Management - iSPASM
David Hasan

16h00-16h15
Break






 

16:15

AVM

16h15-16h27    
Why AVMs    
Ivan Radovanovic

16h30-16h42
Biomechanics of AVM
Ali Alaraj

16h45-16h57
Perspectives on robotics and digital technologies in neuro intervention

Vitor Mendes Pereira

17h00-17h12
Surgical treatment of AVM using Mixed Reality
Julien Haemmerli

17h15-17h30
Closing remarks
Karl Schaller & Philippe Bijlenga

17h30-18h30
Informal discussion & demos in the lobby    

19h30
Lake Dinner - Restaurant de la Plage


Organizers

Prof.
Bijlenga Philippe
Associate Professor in Neurosurgery at University of Geneva and Geneva University Hospital
Dr.
Haemmerli Julien
Neurosurgeon, Chief resident, HUG
Prof.
Schaller Karl
Professor and chair of neurosurgery and dept. of clinical neurosciences, HUG
Prof.
Hirsch Sven
Professor for computational health Head of Center for Computational Health, Institute of Computational Life Sciences, ZHAW
Dr.
Morel Sandrine
Senior researcher in clinical sciences and biology ADB management AneuX Biobank management
Prof.
Machi Paolo
Associate Professor Head of Interventional Neuroradiology Geneva University Hospital Head of Brain Endovascular Therapeutics R&D Lab
Dr.
Carrera Emmanuel
Associate Doctor, Neurovascular Unit, HUG

Contact