

The Interdisciplinary Cerebrovascular Symposium has become a premier meeting, gathering experts with different backgrounds: geneticists, biologists, clinicians, engineers and more recently, data analysts and modellers using AI with a common aim to better understand cerebrovascular pathophysiology and develop new tools to diagnose and treat cerebrovascular diseases. The first ICS took place in Geneva in 2004 and was organised by Prof Daniel A. Rüfenacht, Prof Pedro Lylyk and Prof Makoto Ohta.
The 2023 opus will cover physiology of the cerebrovascular autoregulation and implications in ischemic and haemorrhagic stroke, as well as mechanisms of vessel wall remodelling, aneurysm formation and progression, arterio-venous malformation and arterio-venous fistula natural history modelling and treatments, as well as discussions on cavernous angioma, vasospasm, hydrocephalus and cerebrovascular disautonomy induced by trauma. The sessions will focus on key questions addressed by experts from different backgrounds ending with a moderated roundtable discussion. It has been decided to leave enough time between the sessions and organise social events to promote collaborations.
Prof. Philippe Bijlenga, Prof. Sven Hirsch, Dr. Sandrine Morel, Prof. Paolo Machi, Dr Emmanuel Carrera, Dr. Julien Haemmerli, Prof. Karl Schaller
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The meeting will not be streamed.
Credits: 24 credits CME
Price:
Congress Registration: CHF 800.-
Friday night dinner CHF 100.-
Saturday night dinner CHF 100.-
Forum Geneva
Rue de Lausanne 11-19
1201 Geneva
Forum Geneva
Rue de Lausanne 11-19
1201 Genève
Suisse
8h30
Welcome
8h30-9h15
Cerebrovascular pathology major challenges and tools to succeed
Prof. Jonathan Rosand, neurologist, clinician-scientist and Professor of Neurology, Harvard Medical School.
9h30-9h42
Federating and data share in clinical neurosciences
Philippe Ryvlin
09h45-09h57
Genetics of ischemic stroke
Stéphanie Debette
10h00-10h12
Anatomical Tracings of Lesions After Stroke (ATLAS) 5 key messages
Thomas Wälchli
10h15-10h27
Blood biomarkers of underlying stroke etiology
Mira Katan
10h30-10h42
Molecular mechanisms of different types of stroke from expression profiling of retrieved thrombi
Vincent Tutino
10h45-11h00
Break
11h00-11h12
Genetic cause of childhood stroke
Joel Fluss
11h15-11h27
ER-mitochondria contact sites: a potential therapeutic target for ischemic stroke
Yves Gouriou
11h30-11h42
Cerebrovascular unit, blood brain barrier and ischemia
Susanne Wegener
11h45-11h57
Mathematical models of the cerebral microcirculation and oxygen transport to tissue
Stephen J Payne
12h00-12h15
Break
12h15-12h27
Effective and ineffective medical and interventional treatments of vertebral artery ischemic disease
Patrik Michel
12h30-12h42
Surgical options for extracranial vertebral artery ischemic disease
Fady Charbel
12h45-12h57
Future directions in medical VR training: Challenges and opportunities
Paul Zikas/Steve Kateros
13h00-13h12
Personalised solution for patient care, education and developments
Mathieu Sanchez
13h15-14h00
Lunch & Poster Discussions
14h00-14h45
Degenerative brain diseases and effect on microcirculation
Hugh Markus
15h00-15h12
Genetics of ICH and ERICH study
Stacie Demel
15h15-15h27
Causal ICH classification (CLAS-ICH)
Martina Göldlin
15h30-15h42
Minimally invasive hematoma removal
Raphael Guzman
15h45-16h15
Break
16h15-16h27
Natural history and clinical management
Philipp Damman
16h30-16h42
Brain stem cavernoma management
Amir Dehdashti
16h45-16h57
Cavernoma inflammation and microbiot
Andrea Cardia
17h00-18h30
Informal discussion & demos in the lobby
Free evening
8h15
Welcome
Gabriel Rinkel
09h30-09h42
Genetics of intracranial aneurysms
Mark Bakker
09h45-09h57
Primary cilia control endothelial permeability by regulating expression and location of junction proteins
Mannekomba Diagbouga
10h00-10h12
Intracranial aneurysm, sex-dependent characteristics
Sandrine Morel
10h15-10h27
Sub Arachnoïd Haemorrhage Flora Japan Project
Akio Morita
10h30-11h00
Break
11h00-11h12
Genetics of familial aneurysm
Richard Redon
11h15-11h27
Integrating data to model a multifactorial disease - ontology and database representation
Alban Gaignard
11h30-11h42
Decision upport using Bayesian networks
Georg Spinner
11h45-11h57
Clinical management of unruptured intracranial aneurysms: lessons learned from the pathobiology of the aneurysm wall
Joanna Frösen
12h00-12h15
Break
12h15-12h27
Synthetic database of arterial network and its variability
Hitomi Anzaï
12h30-12h42
Willis Polygon geometry
Norman Juchler
12h45-12h57
Experiment-based super-resolution in intracranial aneurysms using direct data assimilation
Franziska Gaidzik
13h00-13h12
Cerebral blood flow from MRI
Sepideh Amin-Hanjani
13h15-14h00
Lunch & Poster Blitz
14h00-14h45
Current state of AI in Medicine
Pietro Lio
15h00-15h12
Hemodynamic stress and endothelial responses in cerebral aneurysms
Naoki Kaneko
15h15-15h27
EC cells replication and migration
Makoto Ohta
15h30-15h42
Imaging markers, MRI micelles
Eric Allémann
15h45-15h57
Modelling the mechanobiology of intracranial aneurysm evolution
Paul Watton
16h00-16h15
Break
16h15-16h27
Vessel wall structure changes
Rikka Tulamo
16h30-16h42
Circulating gene expression signatures as molecular markers for intracranial aneurysm detection and risk stratification
Vincent Tutino
16h45-16h57
Emerging hemodynamic markers of (un)stable aneurysms: Refined ingredients or just more alphabet soup?
David Steinman
17h00-17h12
Ultrastructural modeling of wall-thinning and thickening process of intracranial aneurysms
Takanobu Yagi
17h30-18h30
Informal discussion & demos in the lobby
19h30
Dinner Place Neuve - Lyric Restaurant
8h15
Welcome
Alfons Hoekstra
09h30-09h42
Biomechanics of IA rupture
Anne Robertson
09h45-09h57
Intravascular Imaging: High resolution microscopy of the cerebrovasculature and beyond
Matt Gounis
10h00-10h12
Genetics of SAH outcome
Ben Gaastra
10h15-10h27
Life experience regarding intracranial aneurysms management
Nobuyuki Sakai
10h30-11h00
Break
11h00-11h12
Initial experience using the eShunt device for the treatment of Normal Pressure Hydrocephalus. (NPH)
Charles Matouk
11h15-11h27
Water and solute dynamic in the brain
Stephen J Payne
11h30-11h42
Craniospinal Compliance. Original conception, 50 years of lessons learned, and new approaches for non-invasive measurement
Andreas Spiegelberg
11h45-11h57
Deferiprone Iron chelation to improve Outcome after SAH - UDISCO
David Hasan
12h00-12h15
Break
12h15-12h25
Beyond the border. Dual training in neurovascular surgery
Anatoly V. Bervitskiy
12h25-12h35
Novel thin-film implants for the treatment of intracranial aneurysms
Prasanth Velvaluri
12h35-12h45
A novel method for brain aneurysms CFD analysis after flow diverter stent implantation based on micro-CT reconstruction
Philippe Reymond
12h45-12h55
Intraoperative LASER Speckle contrast imaging to assess vessel flow in neurosurgery
Johannes Goldberg
12h55-13h05
Coincidental cerebral aneurysms and intracranial tumours
Oleg M. Andrushkevich
13h05-13h15
TBC
Janneck Stahl
13h15:14h00
Lunch & Poster Discussions
Jay Humphrey
15h00-15h12
Genetics of vasospasm and DCI in aneurysmal subarachnoid hemorrhage
Elisa Cuadrado-Godia
15h15-15h27
Cerebrovascular vasospasm modelling
Giulia Pederzani
15h30-15h42
CBF autoregulation after SAH: do we need it at all ?
Marek Czosnyka
15h45-15h57
Induced Suppression of Platelets Activity in aSAH Management - iSPASM
David Hasan
16h00-16h15
Break
16h15-16h27
Why AVMs
Ivan Radovanovic
16h30-16h42
Biomechanics of AVM
Ali Alaraj
16h45-16h57
Perspectives on robotics and digital technologies in neuro intervention
Vitor Mendes Pereira
17h00-17h12
Surgical treatment of AVM using Mixed Reality
Julien Haemmerli
17h15-17h30
Closing remarks
Karl Schaller & Philippe Bijlenga
17h30-18h30
Informal discussion & demos in the lobby
19h30
Lake Dinner - Restaurant de la Plage
8h30
Welcome
8h30-9h15
Cerebrovascular pathology major challenges and tools to succeed
Prof. Jonathan Rosand, neurologist, clinician-scientist and Professor of Neurology, Harvard Medical School.
9h30-9h42
Federating and data share in clinical neurosciences
Philippe Ryvlin
09h45-09h57
Genetics of ischemic stroke
Stéphanie Debette
10h00-10h12
Anatomical Tracings of Lesions After Stroke (ATLAS) 5 key messages
Thomas Wälchli
10h15-10h27
Blood biomarkers of underlying stroke etiology
Mira Katan
10h30-10h42
Molecular mechanisms of different types of stroke from expression profiling of retrieved thrombi
Vincent Tutino
10h45-11h00
Break
11h00-11h12
Genetic cause of childhood stroke
Joel Fluss
11h15-11h27
ER-mitochondria contact sites: a potential therapeutic target for ischemic stroke
Yves Gouriou
11h30-11h42
Cerebrovascular unit, blood brain barrier and ischemia
Susanne Wegener
11h45-11h57
Mathematical models of the cerebral microcirculation and oxygen transport to tissue
Stephen J Payne
12h00-12h15
Break
12h15-12h27
Effective and ineffective medical and interventional treatments of vertebral artery ischemic disease
Patrik Michel
12h30-12h42
Surgical options for extracranial vertebral artery ischemic disease
Fady Charbel
12h45-12h57
Future directions in medical VR training: Challenges and opportunities
Paul Zikas/Steve Kateros
13h00-13h12
Personalised solution for patient care, education and developments
Mathieu Sanchez
13h15-14h00
Lunch & Poster Discussions
14h00-14h45
Degenerative brain diseases and effect on microcirculation
Hugh Markus
15h00-15h12
Genetics of ICH and ERICH study
Stacie Demel
15h15-15h27
Causal ICH classification (CLAS-ICH)
Martina Göldlin
15h30-15h42
Minimally invasive hematoma removal
Raphael Guzman
15h45-16h15
Break
16h15-16h27
Natural history and clinical management
Philipp Damman
16h30-16h42
Brain stem cavernoma management
Amir Dehdashti
16h45-16h57
Cavernoma inflammation and microbiot
Andrea Cardia
17h00-18h30
Informal discussion & demos in the lobby
Free evening
8h15
Welcome
Gabriel Rinkel
09h30-09h42
Genetics of intracranial aneurysms
Mark Bakker
09h45-09h57
Primary cilia control endothelial permeability by regulating expression and location of junction proteins
Mannekomba Diagbouga
10h00-10h12
Intracranial aneurysm, sex-dependent characteristics
Sandrine Morel
10h15-10h27
Sub Arachnoïd Haemorrhage Flora Japan Project
Akio Morita
10h30-11h00
Break
11h00-11h12
Genetics of familial aneurysm
Richard Redon
11h15-11h27
Integrating data to model a multifactorial disease - ontology and database representation
Alban Gaignard
11h30-11h42
Decision upport using Bayesian networks
Georg Spinner
11h45-11h57
Clinical management of unruptured intracranial aneurysms: lessons learned from the pathobiology of the aneurysm wall
Joanna Frösen
12h00-12h15
Break
12h15-12h27
Synthetic database of arterial network and its variability
Hitomi Anzaï
12h30-12h42
Willis Polygon geometry
Norman Juchler
12h45-12h57
Experiment-based super-resolution in intracranial aneurysms using direct data assimilation
Franziska Gaidzik
13h00-13h12
Cerebral blood flow from MRI
Sepideh Amin-Hanjani
13h15-14h00
Lunch & Poster Blitz
14h00-14h45
Current state of AI in Medicine
Pietro Lio
15h00-15h12
Hemodynamic stress and endothelial responses in cerebral aneurysms
Naoki Kaneko
15h15-15h27
EC cells replication and migration
Makoto Ohta
15h30-15h42
Imaging markers, MRI micelles
Eric Allémann
15h45-15h57
Modelling the mechanobiology of intracranial aneurysm evolution
Paul Watton
16h00-16h15
Break
16h15-16h27
Vessel wall structure changes
Rikka Tulamo
16h30-16h42
Circulating gene expression signatures as molecular markers for intracranial aneurysm detection and risk stratification
Vincent Tutino
16h45-16h57
Emerging hemodynamic markers of (un)stable aneurysms: Refined ingredients or just more alphabet soup?
David Steinman
17h00-17h12
Ultrastructural modeling of wall-thinning and thickening process of intracranial aneurysms
Takanobu Yagi
17h30-18h30
Informal discussion & demos in the lobby
19h30
Dinner Place Neuve - Lyric Restaurant
8h15
Welcome
Alfons Hoekstra
09h30-09h42
Biomechanics of IA rupture
Anne Robertson
09h45-09h57
Intravascular Imaging: High resolution microscopy of the cerebrovasculature and beyond
Matt Gounis
10h00-10h12
Genetics of SAH outcome
Ben Gaastra
10h15-10h27
Life experience regarding intracranial aneurysms management
Nobuyuki Sakai
10h30-11h00
Break
11h00-11h12
Initial experience using the eShunt device for the treatment of Normal Pressure Hydrocephalus. (NPH)
Charles Matouk
11h15-11h27
Water and solute dynamic in the brain
Stephen J Payne
11h30-11h42
Craniospinal Compliance. Original conception, 50 years of lessons learned, and new approaches for non-invasive measurement
Andreas Spiegelberg
11h45-11h57
Deferiprone Iron chelation to improve Outcome after SAH - UDISCO
David Hasan
12h00-12h15
Break
12h15-12h25
Beyond the border. Dual training in neurovascular surgery
Anatoly V. Bervitskiy
12h25-12h35
Novel thin-film implants for the treatment of intracranial aneurysms
Prasanth Velvaluri
12h35-12h45
A novel method for brain aneurysms CFD analysis after flow diverter stent implantation based on micro-CT reconstruction
Philippe Reymond
12h45-12h55
Intraoperative LASER Speckle contrast imaging to assess vessel flow in neurosurgery
Johannes Goldberg
12h55-13h05
Coincidental cerebral aneurysms and intracranial tumours
Oleg M. Andrushkevich
13h05-13h15
TBC
Janneck Stahl
13h15:14h00
Lunch & Poster Discussions
Jay Humphrey
15h00-15h12
Genetics of vasospasm and DCI in aneurysmal subarachnoid hemorrhage
Elisa Cuadrado-Godia
15h15-15h27
Cerebrovascular vasospasm modelling
Giulia Pederzani
15h30-15h42
CBF autoregulation after SAH: do we need it at all ?
Marek Czosnyka
15h45-15h57
Induced Suppression of Platelets Activity in aSAH Management - iSPASM
David Hasan
16h00-16h15
Break
16h15-16h27
Why AVMs
Ivan Radovanovic
16h30-16h42
Biomechanics of AVM
Ali Alaraj
16h45-16h57
Perspectives on robotics and digital technologies in neuro intervention
Vitor Mendes Pereira
17h00-17h12
Surgical treatment of AVM using Mixed Reality
Julien Haemmerli
17h15-17h30
Closing remarks
Karl Schaller & Philippe Bijlenga
17h30-18h30
Informal discussion & demos in the lobby
19h30
Lake Dinner - Restaurant de la Plage
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